For both LDL cholesterol and triglycerides, the
associations were in a direction that could have
contributed to the observed association between
a shorter genetically determined height and an
increased risk of CAD. To investigate this finding
further, we evaluated the quantitative associations
between LDL cholesterol and triglycerides
and the risk of CAD that were reported in
observational studies,19 taking into account regression
dilution.20 We determined that for each
1-SD increase, the risk of CAD was raised on
average by 45% (log odds ratio, 0.37) for the LDL
cholesterol level and by 32% (log odds ratio