Soy oil and palmoil are commonly used for deep frying.However,
it has been a common practice to heat the oil repeatedly, in
order to save the cost. The oil is discarded only if the physical
appearance of the oil deteriorates.11 It has been documented that
consumption of repeatedly heated palm oil causes an increase in
the blood pressure (BP) and impaired endothelium-dependent
vascular relaxation.12 Previous study has shown that consumption
of repeatedly heated soy oil was predisposed to atherosclerosis.
1 Inflammation and oxidative stress are attributed to the
pathogenesis of hypertension and atherosclerosis.12 Hypertension
is related to the disturbance of homoeostasis of thromboxane
A2 (TXA2) and prostacyclin (PGI2).13 The two oxygenated
metabolites of arachidonic acid have potent and contrasting effects
on vascular tone and platelet function.13 Inflammation has
been implicated in pathogenesis of atherosclerosis and has been
shown to be associated with an increase in inflammatory biomarkers
such as an increase in the level of C-reactive protein
(CRP), vascular cell adhesion molecule (VCAM-1) and intercellular
adhesion molecule (ICAM-1).14 Elevation in the lactate
dehydrogenase (LDH) enzyme activity also inindicates the disturbance
in the normal functioning of the heart.15