PPI are widely used and generally perceived as safe; they are often over prescribed, started inappropriately during a hospital stay, and their use extended for long-term duration without appropriate medical indication.10–12 Strid et al. examined the use of acid-suppressant drugs in patients with CKD and concluded that acid-suppression therapy is often prescribed without adequate indication, where PPI were the most common drug class used for acid suppression.13
PPI ใช้กันอย่างแพร่หลายและโดยทั่วไปถือว่าเป็นปลอดภัย