The Heel corporation recommend several supplements that may be helpful for pets with megaesophagus (based upon treatment of a similar condition called achalasia and people) These include Ypsiloheel, Spascupreel, Atropinum comp, Nux vomica Homaccord, and Gastricumeel. Whole food supplements may also be helpful in include the following from Standard Process: Organic Minerals, Cataplex B, and Paraplex. Supplements such as choline which have a direct positive effect on nerves may also be tried; my favorite products is made by MVP Laboratories and is called Choldin.
While the treatment of megaesophagus is usually not successful in curing pets with this disease, with patience in choosing the best therapy for each pet, including feeding the “best” diet for each pet, many dogs will live relatively normal lives with a condition that was often fatal in years past.