สาเหตุของความเครียด
So, it is true that stress can increase risk for cancer development by altering physiology. Putative explanations for the adverse effects of stress include changes in the production of the adrenocorticoid, cortisol, which has been shown to have inhibitory effects on the most well-established tumor suppressor gene, p53 (4). Activation of the glucocorticoid receptor has also been shown to stimulate breast cell proliferation. And, more recently, there has been interesting suggestions that stress can act in a manner that is hormone-independent.