Universal prenatal supplementation with iron or iron+folic acid provided either daily or weekly is effective to prevent anaemia and
iron deficiency at term. We found no evidence, however, of the significant reduction in substantive maternal and neonatal adverse
clinical outcomes (low birthweight, delayed development, preterm birth, infection, postpartum haemorrhage). Associated side effects
and particularly haemoconcentration during pregnancy may suggest the need for revising iron doses and schemes of supplementation
during pregnancy and adjust preventive iron supplementation recommendations.
Universal prenatal supplementation with iron or iron+folic acid provided either daily or weekly is effective to prevent anaemia andiron deficiency at term. We found no evidence, however, of the significant reduction in substantive maternal and neonatal adverseclinical outcomes (low birthweight, delayed development, preterm birth, infection, postpartum haemorrhage). Associated side effectsand particularly haemoconcentration during pregnancy may suggest the need for revising iron doses and schemes of supplementationduring pregnancy and adjust preventive iron supplementation recommendations.
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