As part of an ICBG (International Cooperative Biodiversity Groups) project that aims to identify anti-HIV agents from the plants of Vietnam and Laos,13 Vitex leptobotrys H. Hallier (Lamiaceae) was selected for further bioassay-directed fractionation based on positive results in preliminary screening.
Although steroids, chalcones, and an amine were isolated from this plant species,
no prior antiviral pharmacological report on this plant was recorded.