beads based on chitosan (CH) and cashew gum (CG), were prepared and loaded with an essential oil withlarvicide activity (Lippia sidoides – Ls). CH and CH–CG beads were characterized by scanning electronmicroscopy (SEM), infrared and UV–VIS spectroscopy, thermogravimetric analysis (TGA) and differentialscanning calorimetry (DSC), as well as, regarding their larvicide loading, swelling, in vitro and in vivo releasekinetics. The oil encapsulation was evidenced by FTIR analysis and LS loading ranges from 2.4% to 4.4%. CHbeads duly showed swelling degree (Q) values from 4.0 to 6.7, reaching equilibrium after 30 min, whereascrosslinked CH–CG beads showed lower swelling values, from 0.4 to 3.8, exhibiting a longer equilibrium time.Liquid transport parameters have revealed diffusion coefficient for CH–CG beads, as low as 2×10− 15m2/s.TGA and DSC revealed that CH:CG crosslinked beads are more thermally stable than CH beads. In vitro releasefollows a non-Fickian diffusion profile for both bead types, however, and a prolonged release being achievedonly after beads crosslinking. In vivo release showed that both CH and CH–CG presented a prolonged larvicideeffect. These aforesaid results, indicate that CH–CG beads loaded with LS are efficient for A. aegypti larvalcontrol
Preparation and characterization of chitosan/cashew gum beads loaded with Lippia sidoides essential oil (PDF Download Available). Available from: https://www.researchgate.net/publication/229192121_Preparation_and_characterization_of_chitosancashew_gum_beads_loaded_with_Lippia_sidoides_essential_oil [accessed May 2, 2016].