Even though a few adsorption mechanisms have been reported in the literature and summarized in this review, there should be other mechanisms that will be suitable for other adsorptions. Moreover, the development of materials for adsorption, separation, and removal will be accelerated by a fundamental understanding of mechanisms and interactions. For example, suitable MOFs may be designed for water purification utilizing the plausible mechanisms of adsorption or purification. Since adsorptive removal of hazardous materials from spent water only started recently, there is great scope for studying, developing and applying technique for adsorption and removal with MOFs, with or without modifications to incorporate functionalities.