The study was conducted to investigate the platelet increasing property of Carica papaya leaves juice (CPLJ) in patients with dengue
fever (DF). An open labeled randomized controlled trial was carried out on 228 patients with DF and dengue haemorrhagic fever
(DHF). Approximately half the patients received the juice, for 3 consecutive days while the others remained as controls and received
the standard management. Their full blood count was monitored 8 hours for 48 hours. Gene expression studies were conducted
on the ALOX 12 and PTAFR genes. The mean increase in platelet counts were compared in both groups using repeated measure
ANCOVA. There was a significant increase in mean platelet count observed in the intervention group (