In our study, paracetamol is used as a model system to induce acute hepatotoxicity in Swiss albino mice. Assessment of liver function is made by estimating the activities of serum GPT, GOT, ALP and bilirubin which are present higher concentration
in cytoplasm. When there is hepatopathy, these molecules leak into the blood stream in compliance with the extent of liver damage (Nkosi et al., 2005).