Methoxyflurane anesthesia when concurrent with tetracycline
may cause fatal nephrotoxicity. Warfarin with tetracycline may cause increased anticoagulation. Tetracycline may increase the levels/effects of selected benzodiazeplnes, calcium channel blockers. cisapride. cyclosporine, ergot alkaloids, selected HMG-CoA reductase inhibitors. mirtazapine, nateglinide. nefazodone. pirmozide, quinidine sildenas(and other PDE-5 inhibitors), tacrolimus, venlafaxine, and other CYP3A4 substrates