Ocular hypotensive treatment adherence to ocular hypotensive treatment is vital. Topical prostaglandin analogues such as latanoprost 0.005% eye drops are usually prescribed initially because of their low incidence of side effects and convenient once daily instillation. These drugs increase the uveoscleral outflow of aqueous humour through the ciliary muscle by relaxing the muscle or remodelling the surrounding extracellular matrix (Sharts-hopko and glynn-milley 2009).