.A stereo view of the interactions between genistein and human CFTR’s NBD1–NBD2 heterodimer at the five putative binding sites (top view). NBD1 and NBD2are
represented by ribbons, and colored in cyan (NBD1) and green (NBD2), respectively. The genistein molecules are shown in ball-and-stick mode (blue),and the ATP molecules
are shown in stick mode for reference (yellow). Several residues that are important for interacting with genistein are displayed in stick mode (magenta). The figure was
prepared by UCSF Chimera[37].