FA degradation occur in mitochondria via b-oxidation
The b-oxidation consist of 4 reactions:
Formation of trans-a,b double bond through dehydrogenation by acyl-CoA dehydrogenase
Hydration of the double bond to form 3-L-hydroxyacyl CoA by enoyl-CoA hydratase
NAD+-dependent dehydrogenation of the b-hydroxyacyl-CoA to form b-ketoacyl-CoA by 3-L-hydroxyacyl CoA dehydrogenase