Piracetam has been found to have very few side effects, and those it has are typically "few, mild, and transient."[51] A large-scale, 12-week trial of high-dose piracetam found no adverse effects occurred in the group taking piracetam as compared to the placebo group.[52] Many other studies have likewise found piracetam to be well tolerated.[10][51][53]
Symptoms of general excitability, including anxiety, insomnia, irritability, headache, agitation, nervousness, and tremor, are occasionally reported.[54][55]