Arsenic is a ubiquitous element in the natural environment. The
International Agency for Research on Cancer (IARC) regards inorganic arsenic as a carcinogen with a linear dose response for chronic exposure
Because inorganic As is considered to be more toxic than methylated speciese MMAV and DMAV, the assessment of human health risk associated with As in edible plants or foodstuffs mainly depends on the concentrations of inorganic arsenic. Moreover, Food and Agriculture Organization/World Health Organization (FAO/WHO) has a provisional tolerable weekly intake (PTWI) for inorganic arsenic of 15 mg/kg bodyweight (2.1 mg/kg bodyweight (b.w.)/d) Allowable Daily Intake (ADI) of inorganic As for one person with 60 kg bodyweight would be 126 ng/g. However, the EFSA (European Food Safety Authority) Panel on Contaminants in the Food Chain (CONTAM Panel) suggested that PTWI of 15 mg/kg b.w. established by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) is no longer appropriate as data had shown that inorganic arsenic causing cancer of the lung, urinary bladder and skin had been reported at exposures lower than those reviewed by the JECFA. CONTAM Panel assessed the risks of arsenic in food to human health. The inorganic arsenic exposure from food and water across 19 European countries had been estimated to range from 0.13 to 0.56 mg/kg bodyweight (b.w.) per day for average consumers and from 0.37 to 1.22 mg/kg b.w. per day for 95th percentile consumers. Chinese Government, considering the adverse effects of inorganic As on human health, had issued the maximum levels of inorganic arsenic in foods in GB2762-2005, such as rice flour (150 ng/g), wheat flour (100 ng/g), non-staple cereals (200 ng/g) and vegetables (50 ng/g).
Arsenic is a ubiquitous element in the natural environment. The
International Agency for Research on Cancer (IARC) regards inorganic arsenic as a carcinogen with a linear dose response for chronic exposure
Because inorganic As is considered to be more toxic than methylated speciese MMAV and DMAV, the assessment of human health risk associated with As in edible plants or foodstuffs mainly depends on the concentrations of inorganic arsenic. Moreover, Food and Agriculture Organization/World Health Organization (FAO/WHO) has a provisional tolerable weekly intake (PTWI) for inorganic arsenic of 15 mg/kg bodyweight (2.1 mg/kg bodyweight (b.w.)/d) Allowable Daily Intake (ADI) of inorganic As for one person with 60 kg bodyweight would be 126 ng/g. However, the EFSA (European Food Safety Authority) Panel on Contaminants in the Food Chain (CONTAM Panel) suggested that PTWI of 15 mg/kg b.w. established by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) is no longer appropriate as data had shown that inorganic arsenic causing cancer of the lung, urinary bladder and skin had been reported at exposures lower than those reviewed by the JECFA. CONTAM Panel assessed the risks of arsenic in food to human health. The inorganic arsenic exposure from food and water across 19 European countries had been estimated to range from 0.13 to 0.56 mg/kg bodyweight (b.w.) per day for average consumers and from 0.37 to 1.22 mg/kg b.w. per day for 95th percentile consumers. Chinese Government, considering the adverse effects of inorganic As on human health, had issued the maximum levels of inorganic arsenic in foods in GB2762-2005, such as rice flour (150 ng/g), wheat flour (100 ng/g), non-staple cereals (200 ng/g) and vegetables (50 ng/g).
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