Furthermore, R. nasutus had a potent increasing effect on liver SOD, CAT and GPx activities when compared to diabetic control group. Oxidative stress due to free radical mediated lipid peroxidation has been implicated in the pathogenesis of several diseases including diabetes mellitus. Flavonoids, phenols and lignin precursors are regarded to be beneficial antioxidants as they exhibit scavenging activity of harmful active oxygen species.