In order to prevent dehydration and excessive buildup of exudates and control the water loss from a wound at a suitable
rate, a wound dressing should have essential properties such as WVTR. The optimal WVTR of a wound dressing causes to create an environment with a moisture level ideal wound healing. Fig. 4 shows the water vapor permeability for each sample. The water vapor transmission rate of the pure CS membrane was higher than that of the CS/SF blending membrane and it was decreased with the increasing ratio of SF. ADA fixed membrane showed the lowest water vapor transmission, which is approximately 0.385 of the blank group. According to the literature, human skin transpires water vapor at a rate ranging between 240 and 1920 g/m2 × 24 h, whereas the water vapor transmission rate of uncovered wounds could be in the order of 4800 g/m2 × 24 h [19]. In this study, the lower water vapor transmission rate of the fixed blending membranes would be attributed to the chemical bond between CS and SF materials formed by ADA, resulted in harder for the water vapor to penetrate the membranes. However, it still obtained a water vapor transmission rate to some degree which would provide an adequate level of moisture without risking wound dehydration.
In order to prevent dehydration and excessive buildup of exudates and control the water loss from a wound at a suitable
rate, a wound dressing should have essential properties such as WVTR. The optimal WVTR of a wound dressing causes to create an environment with a moisture level ideal wound healing. Fig. 4 shows the water vapor permeability for each sample. The water vapor transmission rate of the pure CS membrane was higher than that of the CS/SF blending membrane and it was decreased with the increasing ratio of SF. ADA fixed membrane showed the lowest water vapor transmission, which is approximately 0.385 of the blank group. According to the literature, human skin transpires water vapor at a rate ranging between 240 and 1920 g/m2 × 24 h, whereas the water vapor transmission rate of uncovered wounds could be in the order of 4800 g/m2 × 24 h [19]. In this study, the lower water vapor transmission rate of the fixed blending membranes would be attributed to the chemical bond between CS and SF materials formed by ADA, resulted in harder for the water vapor to penetrate the membranes. However, it still obtained a water vapor transmission rate to some degree which would provide an adequate level of moisture without risking wound dehydration.
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