TO experimentally validate whether the MVA pathway can provide c5 units for monoterpene biosynthesis both chemical inhibitor and labeling experiment were
employed in developing latifolia specifically we perturbed the metabolic fluxes of the two plahway by using mevinolin or fosmidomycin specific inhibitors of the MVA and MEP pathway respectively MEV competitively inhibits the HMGR enzyme that catalyzes the formation of DXP into MEP both compound have been successfully used in earlier studies dealing with terpene metabolism.