The effective delivery of therapeutic agents toward alleviating medical conditions is one aspect of polymeric
biomaterials design. Polymeric drug delivery systems are
advantageous because they can be controlled to deliver
drugs efficiently to a localized area.110 The nuances of
such a system may have profound implications on tissue
engineering: nanofiber drug delivery systems may provide
insight into the direct incorporation of bioactive growth
factors into scaffolds. Additionally, drug delivery systems
can be combined with implantable tissueengineering scaffolds to prevent infection while repair and regeneration
occur. The discussion below describes the approaches to
modulate the release of drugs from nanofiber scaffolds,
with an emphasis on antibiotic delivery.