Muscle fatigue is a phenomenon of a great practical importance for all individuals in everyday experience, physically
demanding occupations, and sport. The phenomenon should be particularly taken into account in patients with various
types of disorders affecting the CNS and peripheral neuromuscular apparatus. Despite of importance of the
phenomenon, little is yet known about many fine mechanisms contributing to pure muscle components and the means
available to the CNS to compensate for its effect at least partly. Insufficiently investigated questions in the problem
relate to possibility of interaction of the fatigue effects within a separate muscle and agonistic muscle groups.