A number of imaging procedures can be employed to detect HCC, all of which define the characteristic vascularization
pattern of HCC as the essential diagnostic criterion. Particularly arterial hypervascularization with rapid flushing of contrast medium and relative contrast inversion to the surrounding liver parenchyma is considered to constitute sufficient proof of HCC (LoE 2b) in patients with underlying liver cirrhosis, chronic hepatitis B infection, or NASH (18–20). The contrastenhanced
imaging modalities that can be used include not only CT and MRI but also contrast-enhanced ultrasound (CEUS) (Table 2)