The results showed that the ethanol extract of A. paniculata used in this study were able to increase the proliferation of lymphocyte cells at low concentration (1-16 μg/mL). Other studies have also reported that A. paniculata extract increases the lymphocyte cell proliferation at low concentrations, for examples, A. paniculata dichloromethane extract significantly augments the proliferation of human peripheral blood lymphocytes (hPBL) at low concentrations (Chao & Lin 2010). Aqueous extract of A. paniculata also showed significant increased in cellular immunological indicators such as red blood cells, white blood cells, and thrombocytes at low concentration in Tilapia fish Oreochromis mossambicus (Prasad & Mukthiraj 2011). Furthermore, in vivo studies using animals indicated that A. paniculata extract exhibit a significant increase in blood lymphocyte count in both normal and type 2 diabetic rats (Radhika et al. 2012).