A commercial vaccine based on PCV2a and an experimental vaccinebased on a variant mPCV2b are both effective in protecting pigsagainst challenge with a 2013 U.S. variant mPCV2b strain
first-ever detection of PCV2c in live animals. The peculiar population history and ecological scenario
of feral pigs in the Pantanal coupled with the complex, and still only partially known relationship of feral
pigs with other PCV2 susceptible species (i.e., domestic pigs, wild boars and peccaries), open exciting
questions concerning PCV2 origin and evolution. Overall, the results of the present study led us to form
the following hypothesis: the PCV2 strains found in feral pigs may be the last descent of the strains that
circulated among European pigs in the past, or they may have infected these feral pigs more recently
through a bridge species