A study by Ayo-Yusuf et al. [26] concluded that
hemostatic agents can dissolve the smear layer because of
their acidic properties and also can obturate the dentinal
tubules and demineralize dentinal surface. Granular precipitates,
which remain even after acid-etching, were
noted on surfaces exposed to aluminum chloride hemostatic
agent. The exposure of prepared dentin surface to
hemostatic agents altered its morphology and reduced the
dentin's susceptibility to acid-etching. [25-27]