In univariate analysis using “no antibiotic exposure within
60 days” as reference (Table 4), the association between
antibiotic resistance and time interval since the last day of
previous antibiotic exposure increased rapidly within 10
days, significantly peaked at 11 to 20 days, dropped at 21 to
40 days, and decreased to almost baseline at 40 to 60 days.
Patients with antibiotic-resistant infections were administered
more classes of antibiotics in previous infections.
Furthermore, administration of third- and fourth-generation
cephalosporins for previous infections was associated with
increased incidence of antibiotic-resistant infections; however,
there was no significant association between the
duration of previous antibiotic therapy and the emergence
of antibiotic-resistant infections.
In univariate analysis using “no antibiotic exposure within
60 days” as reference (Table 4), the association between
antibiotic resistance and time interval since the last day of
previous antibiotic exposure increased rapidly within 10
days, significantly peaked at 11 to 20 days, dropped at 21 to
40 days, and decreased to almost baseline at 40 to 60 days.
Patients with antibiotic-resistant infections were administered
more classes of antibiotics in previous infections.
Furthermore, administration of third- and fourth-generation
cephalosporins for previous infections was associated with
increased incidence of antibiotic-resistant infections; however,
there was no significant association between the
duration of previous antibiotic therapy and the emergence
of antibiotic-resistant infections.
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