In case of dual infections with PCV2 and M. hyopneumoniae, it
has furthermore been demonstrated that vaccination against either
one of the two pathogens alone does not reduce the severity of
infection of the respective other pathogen [16]. Consequently, vaccination
against one of the two pathogens alone is not sufficient to
protect animals from dual infections with both pathogens, highlighting
the need and the benefit of combined PCV2-M. hyopneumoniae
vaccines.
In conclusion, this is the first report to show that it is possible to
develop a ready-to-use PCV2 and M. hyopneumoniae vaccine that
can be given as a one dose product.