analyzed, showing that the formulations are highly
stable. Evaluation of polydispersity index shows that
both nanoemulsions were homogeneous and adequate
for topical application.
Conclusion
Evaluation of the antioxidant activity by
DPPH showed a significant inhibition of the DPPH●
by both hydroalcoholic extracts from leafs and stems.
This activity is related to molecules with phenolic
groups able to neutralize free radicals as flavonoids.
flavanones and flavanonols which were detected by
pharmacognostical screening and As can be seen
ambos hydroalcoholic extracts presented in dosage test
phenolic a high concentration of such compounds.
The phase inversion method was efficient
in the preparation of stable nanoemulsions that are
adequate for topical application of these extracts. Even
in the formulation form, the antioxidant activity of the
extracts remained the same as found in their solution,
showing the vehicle do not influence on this action.
The nanoemulsions formulations using hydroalcoholic
extracts from leafs and stems have shown promise in
the development of phytomedicines.
Acknowledgments
This work was financially supported by
Fundação de Amparo a Pesquisa do Estado de Minas
Gerais and CNPq.