The methodological issues in multinational price comparisons and results reported were the principal focus of this review. As seen in the reviewed litera- ture, drug price comparisons differed mostly due to the methodology that was used to assess the data. For example, many researchers used different economic parameters, ones they believed were best suited for conducting their research. However, such discrepancies may cause the data found within different studies to become heterogeneous. In 1993, Andersson published a methodological approach to comparing prices accurately (1). This procedure, however, was intended primarily for policymakers to set socially correct prices that would compare equally with countries that had similar policies and economies. With a general price comparison