The previous studies mainly focused on the adsorption of biological molecules onto inorganic surfaces, while the study of interaction between polymer and quartz is few. In this study, we report the structural and thermodynamic behavior between α-quartz and two common polymers (PMMA and PVA)in dry condition. Equilibrium all atoms molecular dynamics (MD)simulations were used to study the whole system in vacuum. All atoms molecular dynamics simulation is an effective computer