While generally safe for use at recommended doses (1,000 mg per
single dose and up to 4,000 mg per day for adults), acute overdoses
of Paracetamol can cause potentially fatal liver damage and, in rare
individuals, a normal dose can do the same; the risk is heightened by
alcohol consumption. Paracetamol toxicity is the foremost cause of
acute liver failure in the Western world, and accounts for most drug
overdoses in the United States, the United Kingdom, Australia and New
Zealand [7-10].