Millions of people today use herbal therapies along with prescription and non prescription medications. Although
considered natural, many of these herbal therapies can interact with other medications, causing either potentially
dangerous side effects and / or reduced benefits from the medication. Currently, there is very little information
published on herb-drug interactions whilst the use of herbs is progressively growing across the world. As there is
large belief that herbal medicines are safe to use, it needs to be understood that depending on the amount and
potency of the pharmacologic principles contained in the herbal preparation, potential exists for herb-drug
interaction to occur when the herbal product is consumed with the modern day medicine. It should be understood
that herbal preparations contain active phytochemicals in varying proportions which have a tendency like any other
active pharmacological substance to alter the enzymatic systems, transporters and / or the physiologic process. The
intent of this review is to update on some imminent issues that may arise if the modern medicine is mixed with a
suspecting herbal preparation. These situations may arise in our daily lives due to the lack of strict adherence to
regular drug prescription practices, unabated use of over the counter drug products and / or self prescription
practices. Health-care practitioners should caution patients against mixing herbs and pharmaceutical drugs.