Nelson Sizer, ran the phrenological business and publishing house Fowlers & Wells in New York City. Meanwhile, Lorenzo spent much of his life in England where he initiated the famous phrenological publishing house, L.N Fowler & Co., and gained considerable fame with his phrenology head (a china head showing the phrenological faculties), which has become a symbol of the discipline.[50] Orson Fowler was known for his octagonal house.