When there is a family history of congenitally missing teeth, asymmetric loss of primary teeth, over-retention of deciduous lateral incisors and canines, lack of developmental canine bulge,or impacted maxillary canines, the possibility of missing lateral
Early investigation is especially important due to the higher association of congenitally
missing or peg-shaped lateral incisors with these anomalies. incisors should be immediately investigated.