The new generation of reproductive management
tools has reached recent developments to eliminate
detection of estrus and increase cattle handling efficiency.
These tools, based on sequential PGF2a and GnRH administrations,
or its analogues, before TAI, are focusing on both
corpus luteum and follicle control [6], resulting in
economical and practical protocols to synchronize ovulation
[7]. Recent strategies include P4 intravaginal supplementation
as part of classic synchronization protocols for
TAI, such as Ovsynch, and several studies have demonstrated
increased pregnancy rate (PR), up to 40% at first AI
in dairy cows [8–10]. This controlled internal drug release
(CIDR) device can also synchronize the return-to-estrus of
nonpregnant cows