Taken together our results underscore the importance of
newts in the study of lens regeneration. However, the fact
that there is a time window in which the axolotl can actually
regenerate the lens provides an excellent comparative
addition to the study of lens regeneration. Recently, the
transcriptome of newt lens regeneration has been completed
(unpublished) as well as similar studies during axolotl
limb regeneration [13]. Thus, this technology could be
of great value to regeneration studies. It will be of great
interest to compare, in the future, the transcriptome of
lens regeneration in axolotl (permissive and non-permissive
stages) with the newt transcriptome of the dorsal and
ventral iris. Such analysis can pinpoint crucial regulation
underlying induction of lens regeneration.