Investigation of the optimal flow rates of feed solution is
significant for the separation of target compounds across HFSLM for
better recovery and scaling-up of the process [45]. The relationship
between the percentage of extraction and stripping of amoxicillin at
different flow rates of feed and stripping solutions which operated a
counter-flow pattern was reported by adjusting flow rates at 50, 100,
150, 200, 250 and 300 mL/min. Results are illustrated in Fig. 8.
The results indicated that by using a flow rate of feed solution of
100 mL/min, the extraction of amoxicillin reached the highest
percentage of about 85.21%. On the other hand, higher flow rates
result in less resident time of the solutions with the extractant
(aliquat 336) or less contact time of the relevant molecule in the
reaction in the HFSLM process. For instance, at too high a flow rate
(especially at 300 mL/min) the membrane system may deteriorate.
This can be seen from both poor liquid membrane stability and lower
percentage of extraction [46]. Therefore, it can be concluded that the
flow rates of feed solutions play an important role in the percentages
of extraction and stripping of amoxicillin.
Investigation of the optimal flow rates of feed solution issignificant for the separation of target compounds across HFSLM forbetter recovery and scaling-up of the process [45]. The relationshipbetween the percentage of extraction and stripping of amoxicillin atdifferent flow rates of feed and stripping solutions which operated acounter-flow pattern was reported by adjusting flow rates at 50, 100,150, 200, 250 and 300 mL/min. Results are illustrated in Fig. 8.The results indicated that by using a flow rate of feed solution of100 mL/min, the extraction of amoxicillin reached the highestpercentage of about 85.21%. On the other hand, higher flow ratesresult in less resident time of the solutions with the extractant(aliquat 336) or less contact time of the relevant molecule in thereaction in the HFSLM process. For instance, at too high a flow rate(especially at 300 mL/min) the membrane system may deteriorate.This can be seen from both poor liquid membrane stability and lowerpercentage of extraction [46]. Therefore, it can be concluded that theflow rates of feed solutions play an important role in the percentagesof extraction and stripping of amoxicillin.
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