Fish is one of the most frequent causes of immunoglobulin E
(IgE)-mediated food allergy. Its prevalence in the regular population
has been estimated to be around 0.2–0.6% (Sicherer, 2011). Symptoms
appear within 60 min of exposure and include acute and generalized urticaria,
nauseas, vomiting, abdominal cramps, diarrhea, wheezing and
asthma (Jeebhay et al., 2001). In the most severe cases, anaphylaxis
shock can potentially be life threatening (Sampson, 2003). To guarantee
the security to the consumers, a number of regulations in terms of food
allergy have been implemented (Directive 2007/68/EC). In the European
Union, these regulations compel the producers to label the fourteen food
allergens, including fish and products thereof, when these have been intentionally
introduced in the foodstuffs. However, some products on the
market could contain traces of allergens due to cross-contaminations
during the food manufacturing processes. As a consequence, accurate,
sensitive and fast detection methods that permit the direct recognition
of allergens in food samples are highly recommendable.