The management of P. aeruginosa UTI (ie, bacteriuria accompanied by symptoms consistent with UTI) involves antibiotic administration as well as correction of obstruction and removal of an indwelling catheter, if present. When P. aeruginosa UTI occurs in a patient with a chronic indwelling bladder catheter, eradication of the organism is usually impossible without catheter removal. If needed, the catheter should be replaced at the outset of antibiotic therapy.