Swelling of the abdomen (belly): Leukemia cells can collect in the liver and spleen,
making them bigger. This might be noticed as a fullness or swelling of the belly. The
lower ribs usually cover these organs, but when they are enlarged the doctor can often
feel them.
Loss of appetite and weight loss: If the spleen and/or liver get big enough, they can
press against other organs like the stomach. This can make the child feel full after eating
only a small amount of food, leading to a loss of appetite and weight loss over time.