The reaction is carried out under
moderate temperatures, thus the catalyst and process temperature
do not degrade the reactor material. Also, unlike chemical catalysis
which works better with methanol, enzymes seem to prefer
ethanol. In the case of chemical catalysis, the high temperature
necessary in the process improves the miscibility between oil and
methanol, while in the case of biocatalysis, the reaction is carried
out at lower temperatures at which the miscibility of methanol in
oil is very poor [23–25]