Freeze-dried juice and ethanolic extracts of fresh leaves. Fresh Thai noni leaves (1 kg) were crushed in a juice extractor filtered and lyophilized, to give a freeze-dried juice extract of fresh leaves (3.72%, F1). The crushed leaves were then macerated with ethanol at room temperature for 72 hours. The filtrate was evaporated to dryness by a rotary evaporator to give an ethanolic extract of fresh leaves (2.6%, F2).