Three out of six also reported a faster
epithelialization process with honey [37–39] and only two
trials found a stimulating effect on the formation of healthy
granulation tissue [40,41].
In four RCTs honey was compared to silver sulphadiazine
(SSD). Remarkably, in two out of four trials honey even had a
statistically significant better antibacterial effect in comparison to SSD; and in all four trials honey established a
statistically significant faster wound healing in comparison
to SSD, which still is considered the worldwide standard to
date (Tables 4 and 5)