Secondary school studies of brain research can be adapted to primary classrooms. Primary school studies such as the Dry Creek study of Caine and Caine (Caine & Caine, 1995), Wolfe and Nevills studies in reading for PreK-3 (Wolfe & Nevills, 2004) and Kagan's multidimensional learning program which includes multiple intelligences (Kagan & Kagan, 1998) provide sufficient data to warrant change in curriculum with best practices of BBR in reading. Current brain-based learning can be synthesized by educators to create literacy environments which best meet the needs of diverse students.