In 1971, Fathalla developed the “incessant ovulation theory,” which held that constant damage, via oxidative stress, and repair of the ovarian epithelium after each cycle of ovulation led to an increased chance of tumor development.
In 1971, Fathalladeveloped the “incessant ovulation theory,” whichheld that constant damage, via oxidative stress, andrepair of the ovarian epithelium after each cycleof ovulation led to an increased chance of tumordevelopment.