Absorption (oral exposure)
Dorough (1968) analyzed carbofuran metabolism in the rat (strain and numbers of animals
dosed were not stated) after single oral doses of carbonyl-14C-carbofuran (0.4 mg/kg) or ring
14C-carbofuran (4 mg/kg). Measurements of radioactivity in urine, feces and, for carbonyI-14Ccarbofuran, expired air (the hydrolysis of ring-14C-carbofuran was not expected to generate
14CO
2) were carried out at designated times. Clinical signs were evident at the higher dose,
which was near the LD
50.