The first symptoms are usually of gastro-enteritis: vomiting,
diarrhoea, abdominal pain, loss of appetite, depression and
dehydration. It will take a few days for the dog to display
the symptoms associated with the loss of red blood cells:
pale mucous membranes, rapid respiratory rate, difficulty
to breath, lethargy, dark coloured urine – reddish or brown,
jaundice, weakness, rapid heart rate. Haematology may
reveal neutrophilia, lymphopenia, Heinz-body anaemia and
methaemoglobinaemia.