Experiment 1
The plasma and tissue corticosterone concentrations before and following injection of ACTH are shown in Figure 2. Plasma concentrations of corticosterone were significantly (P < 0.05) greater 15 min, 30 min, and 60 min after injection of ACTH than before injection ( Fig. 2). In contrast, the plasma concentrations of corticosterone were significantly (P < 0.05) decreased 90 min, 120 min, 150 min, and 180 min after ACTH injection than before injection.