Historically, most of the drugs are derived from natural products. This country, due to its extensive territory,variety of climates and soils, is privileged in the biodiversity of native plants, as can be observed especially in the are as of the Atlantic Rain Forest and Brazilian Cerrado, affording conditions for great chemical diversity in the plants of the sebiomes. This study was conducted as part of our on going bio prospecting program, Biota-FAPESP, with the aim of discovering potential antifungal compounds that could be useful for the development of new tools for the control of infectious diseases